Join forces with researchers to help advance the understanding and treatment of autism. There are studies in our area that are ongoing and asking for participants.
These studies are critical to the advancement of therapeutic and educational tools that help our children. In choosing which studies may be appropriate for your child, read carefully the criteria to make sure your situation matches that of the study.
Each study provides contact information: please contact the study directly for more information on each.
Research Study: The Aviation Study
The Aviation study is a clinical trial of an experimental drug called R05285119, which is being developed as a possible treatment to improve social behavior and communication in people with autism spectrum disorder (ASD). Autism spectrum disorder is a group of brain development disorders that causes persistent difficulties in social communication and social interaction. Currently, there are no medications available to treat these core symptoms of ASD such as social behavior and communication deficits. R05285119 works by blocking a brain receptor of a hormone (the vasopressin receptor) that is associated with control of socialization, stress, anxiety, affection and aggression.
Participants are aged 5-17 with a diagnosis of ASD. Participation lasts for up to 39 weeks and for 24 of those weeks, participants will take daily doses of either the investigational study drug or a placebo (a look-alike) that contains no medicine. Participants and their parent or guardian will visit a study clinic around once every 6 weeks (about 7 times in total).
For more information please contact CANDI at 774-455-4100 or ChildResearch@umassmed.edu
Docket # H00012137
University of Massachusetts’ Child and Adolescent Neuro Development Initiative -CANDI
Learn more by reading about CANDI in their Brochure
UMass CANDI Study – Brain Imaging: A research study for Boys with Autism Spectrum Disorder or Typical Development.
CANDI Research Study: MRI with Children and Adolescents diagnosed with Fragile X or Down Syndrome
Docket # H00002894
The Child and Adolescent Neurodevelopment Initiative (CANDI) at the University of
Massachusetts Medical School is conducting a research study focused on Magnetic
Resonance Imaging (MRI) with children diagnosed with Fragile X or Down Syndrome.
Purpose of the Study
This study is sponsored by the University of Massachusetts Center for Clinical and
Translational Science. The purpose of the study is to determine if we can find ways to help
children undergo MRI without needing to be sedated. We are especially interested in
learning ways to help children with developmental disabilities, such as Fragile X syndrome
and Down syndrome with having an MRI. We also hope to learn more about the features of
the brains of children and adolescents aged 7-17 with Fragile X or Down syndrome.
Participation in this study will last up to approximately 1½ months and requires 2 visits to the
University of Massachusetts Medical School. There will also be some activities that for you
to use at home with your child to prepare him or her for MRI. These activities take about 10
to 15 minutes and can be repeated as often as you feel necessary. For each visit to the
office, a small payment will be offered to offset travel expenses. All study-related evaluations
are provided at no cost.
Males or females between 7 and 17 years of age
Diagnosis of Fragile X syndrome or Down syndrome
Parent willing to assist with desensitization activities at home
If you are interested in learning more about this study, please contact:
Child and Adolescent Neurodevelopment Initiative (CANDI)
University of Massachusetts Medical School
Biotech One, 365 Plantation Street, Suite 100
Worcester, MA 01605-2397
(508) 856-5896 or ChildResearch@umassmed.edu
Boston Children’s Hospital
Study Name: Investigations of Neuroplasticity in Autism Spectrum Disorders
What is this study about? The main purpose of this study is to investigate brain plasticity in children with Autism Spectrum Disorder (ASD). Research suggests that during development the brains of individuals with ASD may change in response to their experiences differently than the brains of typically developing individuals. We want to understand why and how this difference may contribute to the symptoms of ASD. In this study, we will measure brain plasticity with transcranial magnetic stimulation (TMS). TMS is a way to noninvasively activate specific brain areas through the scalp, and it has been used for years in neurology and psychiatry.
How much time does it take? The study involves four visits to Boston Children’s Hospital that last between 2-4 hours.
Who can be in the study? Children ages 6-16 with a diagnosis of Autism Spectrum Disorder.
Who do I contact if I am interested in hearing more about the study? Please contact the study coordinator, Gabrielle Block.
Phone: (617) 667-0206
Beth Israel Deaconess Medical Center
We are currently seeking participants for a brain research study at Beth Israel Deaconess Medical Center.
The main purpose of this study is to compare brain plasticity between people with Autism Spectrum Disorder (ASD), people who are intellectually disabled and people who have typical intellectual function. Research suggests that during development the brains of individuals with ASD may change in response to their experiences differently than the brains of typically developing or intellectually disabled individuals. We want to understand why and how this difference may contribute to the symptoms of ASD.
Brain plasticity is the brain’s ability to change and learn through experience. In this study, we will measure brain plasticity with transcranial magnetic stimulation (TMS).
TMS is a noninvasive way of stimulating the brain. TMS uses a magnetic field to cause activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, we will use TMS to create activity in the brain, and then measure the brain’s response to the activity.
To participate, you must be between the ages of 21-65 and have either:
- A diagnosis of Autism Spectrum Disorder
- An intellectual Disability
- Typical intellectual function
If interested, please contact Gabrielle Block at firstname.lastname@example.org or at 617-667-0206
Mass General Hospital TRANSCEND
Mass General Hospital TRANSCEND Study
Healthy Children/ Children with Autism Spectrum
Disorders Ages 7 to 17
Needed for Research Studies
Boston University Research On Autism and Developmental Disabilities
In the Measuring Autism Potential project we are exploring how children with autism spectrum disorders (ASD) who have very limited verbal skills process language, and how their potential for understanding speech can be reliably measured. Our broader goals are to develop novel methods of assessing children’s receptive language skills that don’t rely on traditional measures (such as pointing), and innovative intervention techniques that are especially suited to enhancing language comprehension in older children with ASD.
Researchers at MIT and Boston University are looking for children and teens ages 5-17 to participate in a study about language.
2-4 visits to MIT for language tests and safe, child-friendly MRI brain imaging.
Receive a picture of your brain and $20-30 per hour in gift cards!
We are on the MIT Campus in Cambridge. We are a short walk from the Kendall/MIT Red Line T stop. We also offer free parking.
At your convenience, days or evenings, weekdays or weekends.
Please contact us any time at:
Web site: Click here.
This research is conducted by Dr. John Gabrieli and Dr.Ken Wexler at the Massachusetts Institute of Technology,
and by Dr. Helen Tager-Flusberg at Boston University.